Development, Performance Evaluation and Clinical Application of A Rapid SARS-CoV-2 IgM and IgG Test Kit Based on Automated Fluorescence Immunoassay
The continued COVID-19 epidemic has made a big impact on well being, economies, and societies everywhere in the world. Though RT-PCR-based nucleic acid detection has been primarily used within the analysis of COVID-19, it’s time-consuming with restricted software situations and should be operated by certified personnel. Antibody take a look at, significantly point-of-care antibody testing, is an acceptable complement to nucleic acid take a look at because it offers fast, transportable, and cost-effective detection of infections.
On this research, a fast antibody take a look at equipment was developed based mostly on fluorescence immunochromatography for the delicate, correct, and automatic detection of IgM and IgG antibodies towards SARS-CoV-2 in human serum, plasma, and complete blood samples inside 10 minutes. The sensitivity, specificity, precision, and stability of the take a look at equipment had been of excellent efficiency.
No cross-activity and no interference was noticed. Within the multiple-center parallel research, 223 samples from hospitalized sufferers had been used to judge the scientific specificity of the take a look at. Each SARS-CoV-2 IgM and IgG achieved a scientific specificity of 98.21%. The scientific sensitivities of SARS-CoV-2 IgM and IgG had been 79.54% and 87.45%, respectively, amongst 733 RT-PCR confirmed SARS-Cov-2 samples. For the mixed IgM and IgG assays, the sensitivity and specificity had been 89.22% and 96.86%, respectively. Our outcomes exhibit that the mixed use of IgM and IgG may function a extra appropriate various detection technique for COVID-19 sufferers, and the developed equipment is of nice public well being significance for the prevention and management of the COVID-19 pandemic.
Comparability of the SARS-CoV-2 Fast Antigen Check to the Actual Star Sars-CoV-2 RT PCR Package
There’s an ongoing want for dependable antigen assays for well timed and simple detection of people with acute SARS-CoV-2 an infection. Utilizing 75 swabs from sufferers beforehand examined constructive by SARS-CoV-2 PCR and 75 swabs from sufferers beforehand examined damaging by SARS-CoV-2 PCR, we investigated the sensitivity and specificity of the SARS-CoV-2 Fast Antigen Check (Roche).
We decided a specificity of 96 %. The assay’s sensitivity with samples with a cycle threshold of < 25, 25 – <30, 30 – <35, and > = 35 was 100%, 95%, 44.8% and 22.2%, respectively. We conclude that sensitivity and specificity of the antigen assay is inferior to the PCR assay. Nevertheless, the antigen assay could also be a fast and simple to carry out various for differentiation of people contagious for SARS-CoV-2 from non-contagious people.
Efficacy of a industrial take a look at equipment to find out early being pregnant in cows utilizing complete blood and blood serum
The target of this research was to find out the efficacy of the Fassisi®BoviPreg visible take a look at equipment (Fassisi®BoviPreg) in figuring out early pregnancies in cows by measuring the pregnancy-associated glycoprotein (PAG) in complete blood and blood serum. The research was performed on 50 cows, the synthetic insemination (AI) dates of which had been designated as day 0.
Being pregnant analysis was carried out with transrectal ultrasonography (USG), and serum samples had been concurrently collected and used with Fassisi®BoviPreg to find out pregnancies on 30 days after AI. The outcomes of the Fassisi®BoviPreg take a look at on serum and complete blood samples, respectively, on 30 days after AI had been as follows: sensitivity, 61.54% and 50.0%; specificity, 79.17% and 75%; accuracy, 70.0% and 62.0%; constructive predictive values, 76.2% and 68.4%; damaging predictive values, 65.5% and 58.1%; false-positive diagnoses, 23.8% and 31.6%; and false-negative diagnoses, 34.5% and 41.9%.
On day 50 after AI, sensitivities had been 63.64% and 50.0%, specificities had been 100.0% and 100.0%, and accuracies had been 75.0% and 65.62% in serum and complete blood, respectively. Larger being pregnant charges had been obtained utilizing Fassisi®BoviPreg in cows with ≥ 5 ng/mL P4 (P < 0.001). In conclusion, the outcomes from the Fassisi®BoviPreg checks on cows on 30 and 50 days after AI confirmed that using blood serum is extra correct and appropriate than that of complete blood. The outcomes additionally confirmed a better confidence stage in specificity 50 days after AI.
Optimum Allocation of COVID-19 Check Kits Amongst Accredited Checking Facilities within the Philippines
Testing is essential for early detection, isolation, and remedy of coronavirus illness (COVID-19)-infected people. Nevertheless, in resource-constrained international locations such because the Philippines, take a look at kits have restricted availability. As of 11 April 2020, there are 11 testing facilities within the nation which were accredited by the Division of Well being (DOH) to conduct testing.
On this paper, we use nonlinear programming (NLP) to find out the optimum proportion allocation of COVID-19 take a look at kits amongst accredited testing facilities within the Philippines that offers an equitable likelihood to all contaminated people to be examined. Heterogeneity in testing accessibility, inhabitants density of municipalities, and the capability of testing services are included within the mannequin.
Our outcomes present that the vary of optimum allocation per testing heart are as follows: Analysis Institute for Tropical Drugs (4.17-6.34%), San Lazaro Hospital (14.65-24.03%), College of the Philippines-Nationwide Institutes of Well being (16.25-44.80%), Lung Heart of the Philippines (15.8-26.40%), Baguio Normal Hospital Medical Heart (0.58-0.76%), The Medical Metropolis, Pasig Metropolis (5.96-25.51%), St. Luke’s Medical Heart, Quezon Metropolis (1.09-6.70%), Bicol Public Well being Laboratory (0.06-0.08%), Western Visayas Medical Heart (0.71-4.52%), Vicente Sotto Memorial Medical Heart (1.02-2.61%), and Southern Philippines Medical Heart (≈ 0.01%).
FAM-Spacer-Phe-CMK FLISP™ Assay Kit |
KF17322 |
Neuromics |
25 Tests |
EUR 291 |
FAM-Spacer-Phe-CMK FLISP™ Assay Kit |
KF17323 |
Neuromics |
100 Tests |
EUR 695 |
FAM-Phe-DAP Serine Protease Assay Kit |
abx299013-25tests |
Abbexa |
25 tests |
EUR 582 |
|
SR-101-Leu-CMK FLISP™ Assay Kit |
KF17321 |
Neuromics |
100 Tests |
EUR 695 |
FAM-Leu-CMK Serine Protease Assay Kit |
abx299011-25tests |
Abbexa |
25 tests |
EUR 566 |
|
OPTIONAL GREEN FILTER (572NM) |
GDBL-GREEN |
CORNING |
1/pk |
EUR 1052 |
Description: Lab Equipment; Axygen Branded EQ |
Polycaspase Assay Kit, green |
KF17200 |
Neuromics |
25 Tests |
EUR 304 |
SR-101-Phe-CMK FLISP™ Assay Kit |
KF17318 |
Neuromics |
25 Tests |
EUR 291 |
SR-101-Phe-CMK FLISP™ Assay Kit |
KF17319 |
Neuromics |
100 Tests |
EUR 695 |
Caspase 1 Assay Kit, green |
KF17201 |
Neuromics |
25 Tests |
EUR 325 |
Caspase 2 Assay Kit, green |
KF17202 |
Neuromics |
25 Tests |
EUR 304 |
Caspase 6 Assay Kit, green |
KF17204 |
Neuromics |
25 Tests |
EUR 304 |
Caspase 8 Assay Kit, green |
KF17205 |
Neuromics |
25 Tests |
EUR 304 |
Caspase 9 Assay Kit, green |
KF17206 |
Neuromics |
25 Tests |
EUR 304 |
Caspase 10 Assay Kit, green |
KF17207 |
Neuromics |
25 Tests |
EUR 304 |
Caspase 13 Assay Kit, green |
KF17208 |
Neuromics |
25 Tests |
EUR 304 |
Malachite Green Phosphate Assay Kit |
abx298878-100Assays |
Abbexa |
100 Assays |
EUR 378 |
|
Malachite Green Phosphate Assay Kit |
POMG-25H |
BioAssay Systems |
2500 |
EUR 275 |
Description: High-throµghput phosphate assay using malachite green method at 620nm. Kit size: 2500 tests. Detection limit: 0.02 µM. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C. |
Malachite Green Phosphate Assay Kit |
Z5030012 |
Biochain |
2,500 assays |
EUR 342 |
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol. |
Caspase 3 & 7 Assay Kit, green |
KF17203 |
Neuromics |
25 Tests |
EUR 304 |
EZCell? Phagocytosis Assay Kit (Green Zymosan) |
K397-100 |
Biovision |
|
EUR 430 |
FAM-Phe-CMK Serine Protease Assay Kit |
abx299010-25tests |
Abbexa |
25 tests |
EUR 566 |
|
FAM-cAMP PDE IV substrate *Green Fluorescence* |
13602 |
AAT Bioquest |
0.5 umol |
EUR 306 |
|
FAM-cGMP PDE V substrate *Green Fluorescence* |
13604 |
AAT Bioquest |
0.5 umol |
EUR 306 |
|
OxiSelect Intracellular ROS Assay Kit (Green Fluorescence) |
STA-342 |
Cell Biolabs |
96 assays |
EUR 635 |
Description: The OxiSelect ROS Assay Kit is a cell-based assay for measuring hydroxyl, peroxyl, and other reactive oxygen species activity within a cell. The assay employs the cell-permeable fluorogenic probe DCFH-DA, which diffuses into cells and is deacetylcated by cellular esterases into the non-fluorescent DCFH (Figure 1). In the presence of ROS, DCFH is rapidly oxidized to highly fluorescent DCF. Fluorescence is read on a standard fluorometric plate reader. |
OxiSelect Intracellular ROS Assay Kit (Green Fluorescence) |
STA-342-5 |
Cell Biolabs |
5 x 96 assays |
EUR 2549 |
Description: The OxiSelect ROS Assay Kit is a cell-based assay for measuring hydroxyl, peroxyl, and other reactive oxygen species activity within a cell. The assay employs the cell-permeable fluorogenic probe DCFH-DA, which diffuses into cells and is deacetylcated by cellular esterases into the non-fluorescent DCFH (Figure 1). In the presence of ROS, DCFH is rapidly oxidized to highly fluorescent DCF. Fluorescence is read on a standard fluorometric plate reader. |
OxiSelect Cellular Antioxidant Assay Kit (Green Fluorescence) |
STA-349 |
Cell Biolabs |
192 assays |
EUR 537 |
Description: The OxiSelect Cellular Antioxidant Assay Kit is a cell-based assay for measuring the activity of an exogenous antioxidant compound within adherent cells. Cells are first cultured in a 96-well black fluorescence cell culture plate until confluent. Then the cells are pre-incubated with a cell-permeable DCFH-DA fluorescence probe dye and the bioflavonoid Quercetin, or the antioxidant sample being tested. After a brief incubation, the cells are washed, and the reaction started by adding the Free Radical Initiator. The Free Radical Initiator creates free radicals that convert the probe to highly fluorescent DCF. The Quercetin inhibits the formation of free radicals, and thus DCF formation, in a concentration dependent manner. |
EZCell? Phagocytosis Assay Kit (Green E. coli) |
K963-100 |
Biovision |
|
EUR 430 |
Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-1895.0001 |
Bachem |
1.0mg |
EUR 321 |
Description: Sum Formula: C49H68N14O15; CAS# [140430-53-1] net |
Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-1895.0005 |
Bachem |
5.0mg |
EUR 1192 |
Description: Sum Formula: C49H68N14O15; CAS# [140430-53-1] net |
Amplite™ Fluorimetric Acetylcholinesterase Assay Kit *Green Fluorescence* |
11401 |
AAT Bioquest |
200 Tests |
EUR 219 |
|
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-2350.0001 |
Bachem |
1.0mg |
EUR 368 |
Description: Sum Formula: C55H80N16O16; CAS# [720710-69-0] net |
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-2350.0005 |
Bachem |
5.0mg |
EUR 1385 |
Description: Sum Formula: C55H80N16O16; CAS# [720710-69-0] net |
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 |
M-2670.0001 |
Bachem |
1.0mg |
EUR 334 |
Description: Sum Formula: C53H70N12O20; CAS# [891198-38-2] net |
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 |
M-2670.0005 |
Bachem |
5.0mg |
EUR 1240 |
Description: Sum Formula: C53H70N12O20; CAS# [891198-38-2] net |
Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
H-2638.0001 |
Bachem |
1.0mg |
EUR 236 |
Description: Sum Formula: C50H77N17O13; CAS# [290362-09-3] net |
Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
H-2638.0005 |
Bachem |
5.0mg |
EUR 853 |
Description: Sum Formula: C50H77N17O13; CAS# [290362-09-3] net |
Amplite™ Fluorimetric Alkaline Phosphatase Assay Kit *Green Fluorescence* |
11953 |
AAT Bioquest |
500 Tests |
EUR 219 |
|
Amplite™ Fluorimetric Beta-Galactosidase Assay Kit *Green Fluorescence* |
12601 |
AAT Bioquest |
500 Tests |
EUR 306 |
|
Amplite™ MMP-3 Activity Assay Kit *Green Fluorescence* |
13512 |
AAT Bioquest |
100 Tests |
EUR 306 |
|
Amplite™ Fluorimetric HDAC Activity Assay Kit *Green Fluorescence* |
13601 |
AAT Bioquest |
200 Tests |
EUR 219 |
|
Cell Meter™ Cell Viability Assay Kit *Green Fluorescence* |
22786 |
AAT Bioquest |
500 Tests |
EUR 219 |
|
Cell Meter™ TUNEL Apoptosis Assay Kit *Green Fluorescence* |
22849 |
AAT Bioquest |
50 Tests |
EUR 306 |
|
OxiSelect Intracellular ROS Assay Kit (Green Fluorescence), Trial Size |
STA-342-T |
Cell Biolabs |
20 assays |
EUR 345 |
Description: The OxiSelect ROS Assay Kit is a cell-based assay for measuring hydroxyl, peroxyl, and other reactive oxygen species activity within a cell. The assay employs the cell-permeable fluorogenic probe DCFH-DA, which diffuses into cells and is deacetylcated by cellular esterases into the non-fluorescent DCFH (Figure 1). In the presence of ROS, DCFH is rapidly oxidized to highly fluorescent DCF. Fluorescence is read on a standard fluorometric plate reader. |
OxiSelect In Vitro ROS/RNS Assay Kit (Green Fluorescence) |
STA-347 |
Cell Biolabs |
96 assays |
EUR 612 |
Description: The OxiSelect In Vitro ROS/RNS Assay provides a sensitive method to detect total reactive oxygen species (ROS) plus reactive nitrogen species (RNS) in a wide variety of sample types. This assay employs a proprietary fluorogenic probe, DCFH-DiOxyQ; the probe is primed with a dequenching reagent to the highly reactive DCFH form. In the presence of ROS and RNS, the DCFH is rapidly oxidized to the highly fluorescent DCF. |
OxiSelect In Vitro ROS/RNS Assay Kit (Green Fluorescence) |
STA-347-5 |
Cell Biolabs |
5 x 96 assays |
EUR 2428 |
Description: The OxiSelect In Vitro ROS/RNS Assay provides a sensitive method to detect total reactive oxygen species (ROS) plus reactive nitrogen species (RNS) in a wide variety of sample types. This assay employs a proprietary fluorogenic probe, DCFH-DiOxyQ; the probe is primed with a dequenching reagent to the highly reactive DCFH form. In the presence of ROS and RNS, the DCFH is rapidly oxidized to the highly fluorescent DCF. |
EZClick? Palmitoylated Protein Assay Kit (FACS/Microscopy), Green Fluorescence |
K452-100 |
Biovision |
|
EUR 490 |
EZClick? Stearoylated Protein Assay Kit (FACS/Microscopy), Green Fluorescence |
K453-100 |
Biovision |
|
EUR 490 |
EZClick? Myristoylated Protein Assay Kit (FACS/Microscopy), Green Fluorescence |
K497-100 |
Biovision |
|
EUR 490 |
Mca-Pro-Lys-Pro-Leu-Ala-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-2225.0001 |
Bachem |
1.0mg |
EUR 371 |
Description: Sum Formula: C61H89N17O17; CAS# [396717-35-4] net |
Mca-Pro-Lys-Pro-Leu-Ala-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-2225.0005 |
Bachem |
5.0mg |
EUR 1321 |
Description: Sum Formula: C61H89N17O17; CAS# [396717-35-4] net |
N-Me-Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-2145.0001 |
Bachem |
1.0mg |
EUR 441 |
Description: Sum Formula: C51H79N17O13; CAS# [396716-07-7] net |
N-Me-Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 |
M-2145.0005 |
Bachem |
5.0mg |
EUR 1675 |
Description: Sum Formula: C51H79N17O13; CAS# [396716-07-7] net |
Amplite™ Fluorimetric Proteasome 20S Activity Assay Kit *Green Fluorescence* |
13456 |
AAT Bioquest |
100 tests |
EUR 306 |
|
Amplite™ Universal Fluorimetric Protease Activity Assay Kit *Green Fluorescence* |
13500 |
AAT Bioquest |
500 Tests |
EUR 219 |
|
Amplite™ Fluorimetric Caspase 3/7 Assay Kit *Green Fluorescence* |
13503 |
AAT Bioquest |
500 Tests |
EUR 306 |
|
Amplite™ Universal Fluorimetric MMP Activity Assay Kit *Green Fluorescence* |
13510 |
AAT Bioquest |
100 Tests |
EUR 306 |
|
Cell Meter™ Fluorimetric Intracellular Peroxynitrite Assay Kit *Green Fluorescence* |
16315 |
AAT Bioquest |
100 Tests |
EUR 350 |
|
Cell Navigator™ Fluorimetric Lipid Droplet Assay Kit *Green Fluorescence* |
22730 |
AAT Bioquest |
200 Tests |
EUR 219 |
|
Amplite™ Fluorimetric Total Thiol Quantitation Assay Kit *Green Fluorescence* |
5524 |
AAT Bioquest |
200 Tests |
EUR 219 |
|
EZClick? Global Protein Synthesis Assay Kit (FACS/Microscopy), Green Fluorescence |
K459-100 |
Biovision |
|
EUR 550 |
Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2 |
M-2520.0001 |
Bachem |
1.0mg |
EUR 321 |
Description: Sum Formula: C49H68N14O15; CAS# [256394-92-0] net |
Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2 |
M-2520.0005 |
Bachem |
5.0mg |
EUR 1192 |
Description: Sum Formula: C49H68N14O15; CAS# [256394-92-0] net |
Cell Meter™ Intracellular Fluorimetric Hydrogen Peroxide Assay Kit *Green Fluorescence* |
11503 |
AAT Bioquest |
200 Tests |
EUR 263 |
|
Cell Meter™ Fluorimetric Mitochondrial Superoxide Activity Assay Kit *Green Fluorescence* |
16060 |
AAT Bioquest |
200 Tests |
EUR 306 |
|
Cell Meter™ Caspase 8 Activity Apoptosis Assay Kit *Green Fluorescence* |
22798 |
AAT Bioquest |
200 Tests |
EUR 219 |
|
Cell Meter™ Caspase 9 Activity Apoptosis Assay Kit *Green Fluorescence* |
22799 |
AAT Bioquest |
200 Tests |
EUR 306 |
|
Amplite™ Rapid Fluorimetric Total Thiol Quantitation Assay Kit *Green Fluorescence* |
5528 |
AAT Bioquest |
200 Tests |
EUR 219 |
|
OxiSelect In Vitro ROS/RNS Assay Kit (Green Fluorescence), Trial Size |
STA-347-T |
Cell Biolabs |
20 assays |
EUR 334 |
Description: The OxiSelect In Vitro ROS/RNS Assay provides a sensitive method to detect total reactive oxygen species (ROS) plus reactive nitrogen species (RNS) in a wide variety of sample types. This assay employs a proprietary fluorogenic probe, DCFH-DiOxyQ; the probe is primed with a dequenching reagent to the highly reactive DCFH form. In the presence of ROS and RNS, the DCFH is rapidly oxidized to the highly fluorescent DCF. |
EZClick? O-GalNAc Modified Glycoprotein Assay Kit (FACS/Microscopy, Green Fluorescence) |
K560-100 |
Biovision |
|
EUR 490 |
EZClickTM Fucose (FucAz) Modified Glycoprotein Assay Kit (FACS/Microscopy, Green Fluorescence) |
K592-100 |
Biovision |
|
EUR 490 |
EZClick? O-GlcNAc Modified Glycoprotein Assay Kit (FACS/Microscopy, Green Fluorescence) |
K714-100 |
Biovision |
|
EUR 512 |
5-FAM |
20-abx095073 |
Abbexa |
-
EUR 523.00
-
EUR 370.00
-
EUR 1274.00
|
|
|
DAP Antibody |
1-CSB-PA262326 |
Cusabio |
|
|
|
Description: A polyclonal antibody against DAP. Recognizes DAP from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
DAP Antibody |
1-CSB-PA01034A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against DAP. Recognizes DAP from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:50-1:200 |
DAP Antibody |
1-CSB-PA006496GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against DAP. Recognizes DAP from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA |
DAP Antibody |
1-CSB-PA007640 |
Cusabio |
|
|
|
Description: A polyclonal antibody against DAP. Recognizes DAP from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/40000 |
DAP Antibody |
1-CSB-PA170450 |
Cusabio |
|
|
|
Description: A polyclonal antibody against DAP. Recognizes DAP from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100 |
DAP Antibody |
35710-100ul |
SAB |
100ul |
EUR 252 |
DAP antibody |
38736-100ul |
SAB |
100ul |
EUR 252 |
DAP Antibody |
43505-100ul |
SAB |
100ul |
EUR 252 |
DAP Antibody |
DF7628 |
Affbiotech |
200ul |
EUR 304 |
Description: DAP Antibody detects endogenous levels of total DAP. |
DAP antibody |
70R-16735 |
Fitzgerald |
50 ul |
EUR 435 |
Description: Rabbit polyclonal DAP antibody |
DAP Peptide |
7389P |
ProSci |
0.05 mg |
EUR 164.75 |
Description: (CT) DAP Peptide |
DAP antibody |
70R-32429 |
Fitzgerald |
100 ug |
EUR 327 |
Description: Rabbit polyclonal DAP antibody |
DAP Antibody |
7389-002mg |
ProSci |
0.02 mg |
EUR 171.82 |
|
Description: DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2). |
DAP Antibody |
7389-01mg |
ProSci |
0.1 mg |
EUR 436.42 |
|
Description: DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2). |
Our outcomes can function a information to the authorities in distributing the COVID-19 take a look at kits. These can be used for proposing further testing facilities and using the accessible take a look at kits correctly and equitably, which helps in “flattening” the epidemic curve.
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